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Chirurgia del tunnel carpale

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C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media
Scritto da BMC Immunology   
AllergologiaBackground:Innate immunity and tissue proliferation play important roles in otitis media (OM), the most common disease of childhood. CJUN terminal kinase (JNK) is potentially involved in both processes.Results:Genes involved in both innate immune ... ...
Assessment of immune cells and function of the residual spleen after subtotal splenectomy due to splenomegaly in cirrhotic patients
Scritto da BMC Immunology   
AllergologiaBackground:The spleen is thought to be central in regulating the immune system, a metabolic asset involved in endocrine function. Overwhelming postsplenectomy infection leads to a mortality rate of up to 50%. However, there is still controversy on p ... ...
Mesenchymal stromal cells reset the scatter factor system and cytokine network in experimental kidney transplantation
Scritto da BMC Immunology   
AllergologiaBackground:In former studies we showed in a rat model of renal transplantation that Mesenchymal Stromal Cells (MSC) prevent acute rejection in an independent way of their endowing in the graft. In this study we investigated whether MSC operate by re ... ...
Leukemia inhibitory factor protects the lung during respiratory syncytial viral infection
Scritto da BMC Immunology   
AllergologiaBackground:Respiratory syncytial virus (RSV) infects the lung epithelium where it stimulates the production of numerous host cytokines that are associated with disease burden and acute lung injury. Characterizing the host cytokine response to RSV in ... ...
T lymphocytes maintain structure and function of fibroblastic reticular cells via lymphotoxin (LT)-B
Scritto da BMC Immunology   
AllergologiaBackground:Although a lot is known about how Fibroblastic Reticular Cells (FRCs) can regulate T lymphocytes (T cells), little is understood about whether or how T cells can regulate FRCs.Results:This study shows that the absence of T cells inhibit ... ...
Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted Chemokines
Scritto da BMC Immunology   
AllergologiaBackground:Mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus and its derivative, everolimus, are potent immunosuppressive and antiproliferative drugs. Inflammatory diseases are characterized by immunological dysfunction, and monocyt ... ...
Granzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells
Scritto da BMC Immunology   
AllergologiaBackground:Granzyme B (GrzB) is a serine proteinase expressed by memory T cells and NK cells. Methods to measure GrzB protein usually involve intracellular (flow cytometry) and extracellular (ELISA and ELISpot) assays. CD8 T cells are the main sourc ... ...
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