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Istopatologia del cuore: febbre reumatica

Reumatologia
Tocilizumab for polymyalgia rheumatica: a first or second line
Scritto da Annals of the Rheumatic Diseases current issue   
Reumatologia

To the Editor:

In the open-label uncontrolled trial recently published in the Annals of the Rheumatic Diseases, Devauchelle-Pensec et al1 showed high efficacy of tocilizumab as ... ...

 
Tocilizumab in recent polymyalgia rheumatica: how can we manage the interleukin-6 blockage
Scritto da Annals of the Rheumatic Diseases current issue   
Reumatologia

Thanks to Dr Moiseev et al1 for their very interesting opinions on the treatment of polymyalgia rheumatica (PMR) with tocilizumab (TCZ). In the TENOR study,... continua Aggiungi commento

 
Issues with anti-Gr1 antibody-mediated myeloid-derived suppressor cell depletion
Scritto da Annals of the Rheumatic Diseases current issue   
Reumatologia

We read with great interest the article ‘Myeloid-derived suppressor cells have a proinflammatory role in the pathogenesis of autoimmune arthritis’ by Chunqing Guo et al.1 In this ... ...

 
Response to: 'Issues with anti-Gr1 antibody-mediated myeloid-derived suppressor cell depletion by Xing et al
Scritto da Annals of the Rheumatic Diseases current issue   
Reumatologia

Myeloid-derived suppressor cell (MDSC) is a heterogeneous myeloid cell population that can broadly be characterised as CD11b+Gr-1+ cells in mice. MDSC can be further classified into two main cell subsets, granulocytic MDSC ( ... ...

 
Does the prevalence of radiographic hand osteoarthritis in patients with HIV-1 infection increase or not
Scritto da Annals of the Rheumatic Diseases current issue   
Reumatologia

Hand osteoarthritis (HOA) is a heterogeneous disease with the involvement of different joints and varying levels of symptoms. Recent studies showed that the prevalence of HOA varied with gender, age and different hand joints.... continua Aggiungi commento

 
Response to: 'Does the prevalence of radiographic hand osteoarthritis in patients with HIV-1 infection increase or not by Luo et al
Scritto da Annals of the Rheumatic Diseases current issue   
Reumatologia

We thank Luo et al1 for their interest in our work demonstrating for the first time that patients with HIV-1 infection display radiographic hand osteoarthritis (HOA) more frequently than the ... ...

 
Why methotrexate suboptimal dosing is a potential source of bias in biologic drugs clinical trials
Scritto da Annals of the Rheumatic Diseases current issue   
Reumatologia

We appreciate the editorial Dr Kremer1 wrote regarding our article2 and we want to clarify some of the issues he raises.

Dr Kremer states tha ... ...

 
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