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Pharmacokinetics of nalbuphine hydrochloride extended release tablets in hemodialysis patients with exploratory effect on pruritus
Scritto da BMC Nephrology   
NefrologiaBackground:Uremic pruritus is a common and deleterious condition among hemodialysis (HD) patients. Central gating of ?/? opiate circuitry plays an important role in mediating and countering pruritogenic sensation. The objective of this study was to ... ...
Impaired renal function and associated risk factors in newly diagnosed HIV-infected adults in Gulu Hospital, Northern Uganda
Scritto da BMC Nephrology   
NefrologiaBackground:Screening for renal diseases should be performed at the time of diagnosis of human immunodeficiency virus (HIV) infection. Despite the high prevalence of HIV/AIDS in Northern Uganda, little is known about the status of renal function and ... ...
Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress
Scritto da BMC Nephrology   
NefrologiaBackground:Diabetic nephropathy (DN) is a major cause of Chronic Kidney Disease and End-Stage Renal Disease throughout the world; however, the reversibility of diabetic nephropathy remains controversial. Endoplasmic reticulum (ER) stress plays an im ... ...
Results of a novel screening tool measuring dietary sodium knowledge in patients with chronic kidney disease
Scritto da BMC Nephrology   
NefrologiaBackground:Reducing dietary sodium has potential to benefit patients with chronic kidney disease (CKD). Little research is available defining dietary sodium knowledge gaps in patients with pre-dialysis CKD. We designed a brief screening tool to rapi ... ...
Parathyroid hormone change after cinacalcet initiation and one-year clinical outcome risk: a retrospective cohort study
Scritto da BMC Nephrology   
NefrologiaBackground:Cinacalcet reduces parathyroid hormone (PTH) levels in patients receiving hemodialysis, but no non-experimental studies have evaluated the association between changes in PTH levels following cinacalcet initiation and clinical outcomes. We ... ...
Case report: lupus nephritis with autoantibodies to complement alternative pathway proteins and C3 gene mutation
Scritto da BMC Nephrology   
NefrologiaBackground:Glomerulonephritis is one of the most severe complications of lupus, a systemic disease with multi-organ involvement, with tissue damage produced mainly by complement activation. As a result of this activation, patients with active lupus ... ...
Comparison of quality-of-care measures in U.S. patients with end-stage renal disease secondary to lupus nephritis vs. other causes
Scritto da BMC Nephrology   
NefrologiaBackground:Patients with end-stage renal disease (ESRD) due to lupus nephritis (LN-ESRD) may be followed by multiple providers (nephrologists and rheumatologists) and have greater opportunities to receive recommended ESRD-related care. We aimed to e ... ...
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