Ipsilateral foetal-type posterior cerebral artery is associated with cognitive decline after carotid revascularisation
Scritto da BMC Neurology   
NeurologiaBackground:Stenosis of the internal carotid artery has been associated with cognitive impairment and decline. However, studies testing the effect of carotid revascularisation on cognition have had conflicting results. This may in part be explained b ... ...
Actigraphy as a diagnostic aid for REM sleep behavior disorder in Parkinson¿s disease
Scritto da BMC Neurology   
NeurologiaBackground:Rapid eye movement (REM) sleep behavior disorder (RBD) is a common parasomnia in Parkinson?s disease (PD) patients. The current International Classification of Sleep Disorders (ICSD-II) requires a clinical interview combined with video po ... ...
Improved accuracy in diagnosis for epilepsy with new clinical definition
Scritto da Epilepsy News From Medical News Today   
NeurologiaAn expert task force has created a new definition for epilepsy that refines the scope of patients diagnosed with this brain disease. ... ...
Could Silly Putty help treat neurological disorders
Scritto da Huntingtons Disease News From Medical News Today   
NeurologiaResearchers from the University of Michigan found that a compound in Silly Putty - a children's moulding toy - helped turn stem cells into working motor neurons more efficiently. ... ...
Critical role of TNF-alpha in cerebral aneurysm formation and progression to rupture
Scritto da Journal of Neuroinflammation   
NeurologiaBackground:Alterations in TNF-alpha expression have been associated with cerebral aneurysms, but a direct role in formation, progression, and rupture has not been established.Methods:Cerebral aneurysms were induced through hypertension and a singl ... ...
FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway
Scritto da Journal of Neuroinflammation   
NeurologiaBackground:The accumulation of activated microglia is a hallmark of various neurodegenerative diseases. Microglia may have both protective and toxic effects on neurons through the production of various soluble factors, such as chemokines. Indeed, va ... ...
CXCL12 in astrocytes contributes to bone cancer pain through CXCR4-mediated neuronal sensitization and glial activation in rat spinal cord
Scritto da Journal of Neuroinflammation   
NeurologiaBackground:Previous studies have demonstrated that chemokine CXCL12 and its receptor CXCR4 are critical for pain sensitization, but the mechanisms involved are not clear. In this study, we investigated the specific cellular mechanisms of CXCL12/CXCR ... ...
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